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Search Results for " 6 thioguanine "

3

Compounds

Cat No. Product Name Synonyms Targets
T3089 6-Thioguanine 6-TG,2-Amino-6-purinethiol,2-Amino-6-mercaptopurine,Thioguanine Apoptosis , DNA Methyltransferase , SARS-CoV , Endogenous Metabolite , DUB , Autophagy
6-Thioguanine (2-Amino-6-purinethiol) is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.
T67864 TH1760 MKB NUDIX hydrolase
TH1760 (MKB) is an inhibitor of NUDIX-type 15 (NUDT15, IC50= 25 nM). TH1760 can sensitize cells to 6-thioguanine by increasing the accumulation of 6-thio- (d) GTP in nucleic acids. TH1760 can enhance the anti-leukemia ef...
T70304 CI-898 HCl
CI-898 HCl is a lipophilic antifolate inhibitor of dihydrofolate reductase (DHFR). It has enhanced binding to DHFR in the presence of the cofactor NADPH. Cl-898 HCl inhibits cell growth and halts the cell cycle at the G1...
TargetMol